CLASSIC
In ICU patients with septic shock who have had initial fluid resuscitation, what are the effects and feasibility of a protocol restricting further resuscitation fluid as opposed to standard care?
Continue reading »Tag: Sepsis
VASST
In adult patients with septic shock, does the addition of vasopressin infusion to a norepinephrine infusion compared to a norepinephrine infusion alone decrease mortality rate at 28 days?
Continue reading »VANISH Trial
Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?
Continue reading »BLISS
In adult ICU patients with severe sepsis does the use of continuous infusion (CI) of beta-lactam antibiotics compared to intermittent bolus (IB) improve clinical outcomes?
Continue reading »Ventura
In paediatric patients with septic shock, does adrenaline compared with dopamine reduce 28 day mortality?
Continue reading »STOP-IT
In patients with intraabdominal sepsis and who have received adequate source control, does a fixed short course of antibiotics result in similar treatment success compared to a longer duration of antibiotic therapy?
Continue reading »FEAST
In paediatric patients with severe febrile illnesses, in a resource limited setting, do fluid boluses with albumin vs. saline vs. no fluid boluses affect mortality?
Continue reading »Kumar
In patients with septic shock, what is the relationship between appropriateness of initial empiric antimicrobial therapy and survival?
Continue reading »ProMISe
In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »Sun
In patients with acute kidney injury (AKI) and severe sepsis or septic shock, does extended daily haemofiltration (EDHF) compared with continuous venovenous haemofiltration (CVVHF) reduce time to renal recovery or mortality at 60 days?
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