Tag: Sepsis

ATESS

16 September 2020 Adrian Wong Intensive Care Medicine Leave a comment

In patients with septic shock, does the use of intravenous vitamin C and thiamine compared to standard therapy improve recovery from organ failure?

RECOVERY: COVID-19 dexamethasone

3 July 2020 Celia Bradford Intensive Care Medicine Leave a comment

In hospitalised patients with SARS-CoV-2 infection does dexamethasone in additional to usual care, compared to usual care alone, reduce 28-day mortality?

ACTT-1

In hospitalised adult patients with evidence of lower respiratory tract infection due to COVID-19, is remdesivir superior to placebo in shortening the time to recovery?

FABLED

13 March 2020 Celia Bradford Emergency Medicine, Intensive Care Medicine Leave a comment

In patients with severe sepsis what is the sensitivity of blood cultures taken after the initiation of antimicrobial therapy?

65 Trial

14 February 2020 Celia Bradford Intensive Care Medicine 5 comments

In patients older than 65-years with vasodilatory hypotension receiving vasopressors, does a target mean arterial pressure (MAP) of 60-65mmHg compared with usual care impact mortality?

VITAMINS

19 January 2020 Steve Mathieu Emergency Medicine, Intensive Care Medicine 2 comments

Does treatment with vitamin C, hydrocortisone, and thiamine lead to a more rapid resolution of septic shock compared with hydrocortisone alone?

Vitamin C Sepsis

25 October 2019 Segun Olusanya Intensive Care Medicine, Summaries Leave a comment

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial Fowler AA. JAMA; 2019;322(13):1261-1270 Clinical Question In patients with sepsis and acute respiratory distress syndrome, can intravenous administration of vitamin C, compared to placebo, reduce organ failure scores and biomarkers of inflammation and vascular injury? […]

SCARLET

14 June 2019 George Walker Emergency Medicine, Intensive Care Medicine Leave a comment

In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?