SMART
In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
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READS
For healthcare professionals interpreting chest radiographs, does an educational intervention compared to no educational intervention improve the diagnosis or exclusion of acute respiratory distress syndrome (ARDS)
Continue reading »ELAIN FOLLOW-UP
In adult critically ill patients, with acute kidney injury, does early initiation of RRT compared to delayed initiation of RRT reduce the composite endpoint of MAKE365; consisting of death, RRT and persistent renal dysfunction at one year?
Continue reading »Arulkumaran
In patients who are unplanned admissions to critical care, does the day and time of admission to critical care influence acute hospital mortality?
Continue reading »LIPPSMAck-POP
In patients undergoing upper abdominal surgery (UAS), does the addition of a single pre-op physiotherapy session compared to standard care reduce the rate of post-operative pulmonary complications (PPC)?
Continue reading »BILEVEL-APRV
In mechanically ventilated patients with ARDS, does airway pressure release ventilation (APRV) compared to conventional low tidal volume ventilation (LTV) reduce duration of mechanical ventilation?
Continue reading »ADRENAL
In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
Continue reading »CURE
In patients with acute coronary syndromes without ST elevation, does clopidogrel + aspirin, compared with aspirin alone, reduce a composite outcome of death from cardiovascular causes, acute myocardial infarction and stroke?
Continue reading »Steroids in Sepsis
In patients with septic shock, do corticosteroids compared to placebo reduce mortality?
This is an editorial blog post in anticipation of the ADRENAL trial results to be presented at #CCR18.
COIITSS
In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?
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