PRESERVE

In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Peri-operative Medicine
In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »In critically ill patients undergoing emergency intubation, does the ramped position compared to sniffing position reduce the incidence of oxygen desaturation?
Continue reading »In critically ill patients undergoing intubation, does the use of a pre-intubation checklist compared to no checklist prevent oxygen desaturation or systolic hypotension?
Continue reading »In patients undergoing bowel surgery, does a single dose of dexamethasone compared against standard care reduce nausea and vomiting in the early post-operative period?
Continue reading »In high-risk patients undergoing surgical procedures, does a strategy of targeting individualised systolic blood pressure compared to standard practice reduce organ dysfunction
Continue reading »In adult patients undergoing elective coronary-artery surgery does tranexamic acid (TXA) compared to a placebo increase the risk of death or thrombotic complications within the first 30 days after surgery?
Continue reading »In adults undergoing elective coronary artery graft surgery does the administration of aspirin prior to surgery compared to a placebo result in increased mortality or thrombotic complications?
Continue reading »In patients undergoing non-cardiac surgery, do beta-blockers compared to placebo reduce the composite of death, MI or non-fatal cardiac arrest?
Continue reading »Does the early administration of tranexamic acid (TXA), compared with placebo, reduce death from bleeding in women with post-partum haemorrhage (PPH)?
Continue reading »