APPAC

In patients presenting with acute uncomplicated appendicitis, is antibiotic therapy non-inferior to appendicectomy surgery?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In patients presenting with acute uncomplicated appendicitis, is antibiotic therapy non-inferior to appendicectomy surgery?
Continue reading »In paediatric patients with septic shock, does adrenaline compared with dopamine reduce 28 day mortality?
Continue reading »In critical care doctors, does mulled wine compared to normal saline, improve the sense of well-being and ICU length of stay?
Continue reading »In patients with traumatic brain injury (TBI), does hypothermia (32-35°C) and standard care compared to standard care alone reduce death and major disability at 6 months after injury?
Continue reading »In adult patients with suspected bacterial infections, does procalcitonin-guided antibiotic care compared to usual care reduce patient exposure to antibiotics without increasing mortality?
Continue reading »In adult patients that are in cardiac arrest, do uninterrupted chest compressions compared to chest compressions interrupted for manual ventilation improve survival, neurological recovery or the rate of adverse events?
Continue reading »In older patients (over 80 years) admitted to Intensive Care Units, what factors are predictive of survival with good health-related quality of life?
Continue reading »In patients with aneurysmal subarachnoid haemorrhage does induced hypermagnesaemia reduce the incidence of cerebral artery vasospasm?
Continue reading »In patients with moderate or severe traumatic brain injury does the administration of erythropoietin compared with placebo improve neurological outcome at 6 months after injury?
Continue reading »In intensive care patients who require a central venous catheter (CVC), does the choice of insertion site affect the complication rates?
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