DESIRE

In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?
Continue reading »In patients undergoing cardiac surgery with left ventricular dysfunction, does levosimendan compared to placebo reduce mortality?
Continue reading »In intensive care patients requiring orotracheal intubation, does video laryngoscopy (VL) compared to the Macintosh direct laryngoscope (DL) increase the frequency of first pass intubation?
Continue reading »In patients with LVEF <35% undergoing cardiac surgery does levosimenden compared with placebo reduce the incidence of a composite outcome of: death at day 30; renal replacement therapy at day 30; perioperative myocardial infarct at day 5; and use of mechanical assist device at day 5
Continue reading »In patients who develop acute hypoxaemic respiratory failure after abdominal surgery, does non-invasive ventilation compared to standard oxygen therapy prevent the need for re-intubation?
Continue reading »In patients with cirrhosis and septic shock does terlipressin in comparison with noradrenaline improve haemodynamic parameters?
Continue reading »In high-risk patients receiving contrast medium, does prophylactic hydration with normal saline compared to no prophylaxis impact the rate of contrast-induced nephropathy?
Continue reading »In patients who have undergone major abdominal surgery does the application of high flow nasal cannulae compared with standard oxygen therapy, decrease the incidence of hypoxemia at one hour after extubation?
Continue reading »In adult mechanically ventilated patients, does inhaled heparin compared to inhaled saline or usual care reduce the incidence of ventilator acquired pneumonia (VAP)?
Continue reading »In adult ICU patients, does the use dynamic light therapy compared to normal lighting, reduce the incidence and duration of ICU-acquired delirium?
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