BILEVEL-APRV
In mechanically ventilated patients with ARDS, does airway pressure release ventilation (APRV) compared to conventional low tidal volume ventilation (LTV) reduce duration of mechanical ventilation?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
ADRENAL
In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
Continue reading »CURE
In patients with acute coronary syndromes without ST elevation, does clopidogrel + aspirin, compared with aspirin alone, reduce a composite outcome of death from cardiovascular causes, acute myocardial infarction and stroke?
Continue reading »COIITSS
In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?
Continue reading »ART
In patients with moderate to severe acute respiratory distress syndrome (ARDS) does use of a lung recruitment maneuver associated with positive end-expiratory pressure (PEEP) titration according to the best respiratory-system compliance, compared with a conventional low-PEEP strategy, decrease 28-day mortality?
Continue reading »MoDUS
In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?
Continue reading »PRESERVE
In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »TRICS-III
In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »SSSP2
In Zambian adults with sepsis and hypotension, does a resuscitation protocol implemented early after presentation to the Emergency Department improve in-hospital mortality compared with usual care?
Continue reading »ICE-CUB 2
In critically ill patients aged over 75 years, does a recommendation for systematic ICU admission compared with standard care reduce 6 month mortality?
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