MASTERS

In high-risk patients undergoing major abdominal surgery, does epidural analgesia compared with no epidural analgesia reduce mortality and morbidity?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In high-risk patients undergoing major abdominal surgery, does epidural analgesia compared with no epidural analgesia reduce mortality and morbidity?
Continue reading »Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?
Continue reading »In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?
Continue reading »In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?
Continue reading »In adult critically ill patients receiving pharmacological thromboprophylaxis, does the use of adjunctive intermittent pneumatic compression devices result in a lower incidence of proximal deep vein thrombosis (DVT)?
Continue reading »In adult patients undergoing abdominal surgery, with intermediate-to-high-risk of post-operative pulmonary complications, will an individualised perioperative open-lung ventilation strategy (iPROVE), compared with standard protective ventilation, result in fewer post-operative complications during the first 7 days post surgery
Continue reading »In patients with septic shock, does early low-dose norepinephrine compared with standard care increase shock control at six hours?
Continue reading »In patients who presented to the Emergency Department (ED) with acute dyspnoea, does the addition of lung ultrasound examination compared to standard approach, improve the diagnostic accuracy for acute decompensated heart failure (ADHF)?
Continue reading »In patients undergoing rapid sequence anaesthesia induction, does the use of cricoid pressure vs. a sham procedure, prevent pulmonary aspiration?
Continue reading »In patients with acquired thrombocytopenia purport, does calpacizumab compared with placebo, reduce the time to normalisation of the platelet count?
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