BACC
In hospitalised patients with severe acute respiratory syndrome due to coronavirus 2 (SAR-CoV-2), does tocilizumab compared with placebo, reduce intubation rates or mortality?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
DANMASK-19
In adults in Denmark reported to spend three hours or more outside of the home during the early stages of the COVID-19 pandemic, did a recommendation to wear a surgical face mask, compared with no recommendation to wear a surgical face mask, reduce SARS-CoV-2 infection at one month?
Continue reading »ARREST
In adults suffering out of hospital cardiac arrest (OHCA) presenting with an initial rhythm of VF or pulseless VT, does the implementation of early ECMO facilitated resuscitation compared to standard ACLS resuscitation improve survival to hospital discharge?
Continue reading »RECOVERY: COVID-19 Kaletra
In patients admitted to hospital with COVID-19, does Lopinavir-ritonavir therapy (Kaletra) compared to usual care, reduce 28-day mortality?
Continue reading »ITACTIC
In adult trauma patients presenting with signs of haemorrhagic shock does the utilisation of a viscoelastic haemostatic assay (VHA) augmented transfusion strategy compared to a strategy augmented by conventional coagulation tests (CCT) result in an increased number of patients alive and free of massive transfusion at 24 hours?
Continue reading »REDECAP
In conscious critically ill patients who have had a tracheostomy inserted as part of their ICU stay and have been weaned from mechanical ventilation, does an assessment of readiness for decannulation that is based on suctioning frequency, when compared to an assessment based on tracheostomy capping, result in a shorter time to successful decannulation?
Continue reading »MIDAS
In patients aged > 18 years who were unable to be liberated from vasopressors for 24 hours, did the addition of midodrine when compared to a placebo result in the earlier discontinuation of vasopressors?
Continue reading »ATESS
In patients with septic shock, does the use of intravenous vitamin C and thiamine compared to standard therapy improve recovery from organ failure?
Continue reading »REMAP-CAP
In patients with severe COVID-19, does intravenous hydrocortisone (either as a fixed dose or restricted to when shock is clinically evident) compared with standard care, improve 21-day organ support free days?
Continue reading »LOCO2
In patients with acute respiratory distress syndrome (ARDS), does conservative vs. liberal oxygen reduce death at 28 days?
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