Lilja
In patients with out-of-hospital (OOH) cardiac arrest does a target temperature management (TTM) of 33°C vs. 36°C improve cognitive function
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
Torres
In patients with severe community-acquired pneumonia and high inflammatory response, does the use of corticosteroids compared to placebo improve outcom
Continue reading »ProMISe
In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »Determann
In mechanically ventilated patients without acute lung injury or acute respiratory distress (ALI/ARDS), does lower tidal volume ventilation at 6 ml/kg (Vt-low), compared to conventional tidal volume ventilation at 10 ml/kg (Vt-high), reduce cytokine levels associated with lung injury?
Continue reading »MOnIToR trial
In brain-dead organ donors does the use of protocolised fluid therapy compared to usual care improve the number of organs transplanted?
Continue reading »CRASH-2
In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
Continue reading »RESTORE
Does a nurse-implemented, goal-directed sedation protocol result in fewer ventilator days in children with acute respiratory failure?
Continue reading »VITdAL-ICU
In critically ill patients with low serum vitamin D levels, does high-dose vitamin D supplementation compared with placebo reduce hospital length of stay?
Continue reading »ACURASYS
In patients with moderate-severe ARDS does the early use of a neuromuscular blocking agent improve mortality?
Continue reading »CHEST
In critically ill patients requiring fluid resuscitation, does 6% hydroxyethyl starch (6% HES) compared to 0.9% sodium chloride (Saline) reduce mortality at 90 days?
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