THAPCA-OH

In children suffering an out-of-hospital cardiac arrest, does hypothermia compared to normothermia increase survival with a good neurobehavioural outcome?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Intensive Care Medicine
In children suffering an out-of-hospital cardiac arrest, does hypothermia compared to normothermia increase survival with a good neurobehavioural outcome?
Continue reading »In organ donors, following diagnosis of brainstem death, does therapeutic hypothermia decrease delayed graft function in kidney recipients?
Continue reading »In critically ill adults, does restriction of non-protein calories (permissive underfeeding) compared to standard feeding reduce mortality at 90 days?
Continue reading »Do patients admitted to English NHS hospitals on weekend days, compared to those admitted during week days, have an increased 30-day mortality?
Continue reading »In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial IABP-SHOCK II Trial Investigators.NEJM;2012,367(14)1287-96, DOI: 10.1056/NEJMoa1208410 Clinical Question In patients with acute MI and cardiogenic shock, does intraaortic balloon counterpulsation (IABP) vs. medical therapy alone improve mortality? Design Randomised controlled trial Randomisation performed centrally via internet based program […]
Continue reading »Does the administration of paracetamol reduce mortality in critically ill patients on the Intensive Care Unit?
Continue reading »In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?
Continue reading »In patients with severe traumatic brain injury does monitoring intracranial pressure improve mortality and improve neurological function?
Continue reading »What is the clinical outcome of patients after major non-cardiac surgery in Europe?
Continue reading »