ANNEXA

In healthy adults taking either apixaban (ANNEXA-A) or rivaroxaban (ANNEXA-R) does andexanet alfa compared to placebo normalise anticoagulation?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Intensive Care Medicine
In healthy adults taking either apixaban (ANNEXA-A) or rivaroxaban (ANNEXA-R) does andexanet alfa compared to placebo normalise anticoagulation?
Continue reading »Does early rehabilitation reduce physical impairment and ICU length of stay in critically ill patients?
Continue reading »In adult ICU patients with severe sepsis does the use of continuous infusion (CI) of beta-lactam antibiotics compared to intermittent bolus (IB) improve clinical outcomes?
Continue reading »In paediatric patients with septic shock, does adrenaline compared with dopamine reduce 28 day mortality?
Continue reading »In critical care doctors, does mulled wine compared to normal saline, improve the sense of well-being and ICU length of stay?
Continue reading »In patients with traumatic brain injury (TBI), does hypothermia (32-35°C) and standard care compared to standard care alone reduce death and major disability at 6 months after injury?
Continue reading »In adult patients with suspected bacterial infections, does procalcitonin-guided antibiotic care compared to usual care reduce patient exposure to antibiotics without increasing mortality?
Continue reading »In adult patients that are in cardiac arrest, do uninterrupted chest compressions compared to chest compressions interrupted for manual ventilation improve survival, neurological recovery or the rate of adverse events?
Continue reading »In older patients (over 80 years) admitted to Intensive Care Units, what factors are predictive of survival with good health-related quality of life?
Continue reading »In patients with aneurysmal subarachnoid haemorrhage does induced hypermagnesaemia reduce the incidence of cerebral artery vasospasm?
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