INSTINCT
In patients with necrotising soft tissue infection (NSTI), does the use of intravenous immunoglobulin (IVIG) compared to placebo improve patient reported physical outcomes?
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
EMPIRICUS
In non-neutropenic critically ill patients with sepsis, multiple Candida colonisation, and multiple organ failure exposed to broad-spectrum antibacterials, does empirical micafungin therapy compared to placebo increase invasive fungal infection-free survival at day 28?
Continue reading »Lars Anderson
In adult patients with in-hospital cardiac arrest, is tracheal intubation associated with survival to hospital discharge?
Continue reading »WOMAN Trial
Does the early administration of tranexamic acid (TXA), compared with placebo, reduce death from bleeding in women with post-partum haemorrhage (PPH)?
Continue reading »DESIRE
In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?
Continue reading »CHEETAH
In patients undergoing cardiac surgery with left ventricular dysfunction, does levosimendan compared to placebo reduce mortality?
Continue reading »MACMAN
In intensive care patients requiring orotracheal intubation, does video laryngoscopy (VL) compared to the Macintosh direct laryngoscope (DL) increase the frequency of first pass intubation?
Continue reading »LEVO-CTS
In patients with LVEF <35% undergoing cardiac surgery does levosimenden compared with placebo reduce the incidence of a composite outcome of: death at day 30; renal replacement therapy at day 30; perioperative myocardial infarct at day 5; and use of mechanical assist device at day 5
Continue reading »NIVAS
In patients who develop acute hypoxaemic respiratory failure after abdominal surgery, does non-invasive ventilation compared to standard oxygen therapy prevent the need for re-intubation?
Continue reading »Choudhury
In patients with cirrhosis and septic shock does terlipressin in comparison with noradrenaline improve haemodynamic parameters?
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