OPTALYSE PE
In patients with intermediate risk PE, do low doses of tPA and short durations of ultrasound facilitated catheter directed thrombolysis, result in a reduction in RV:LV diameter at 48 hours?
Continue reading »Category: Emergency Medicine
A collection of TBL summaries relevant to Emergency Medicine
SCARLET
In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?
Continue reading »EXTEND
In patients with acute ischaemic stroke, with salvageable brain tissue, does alteplase compared with placebo, administered between 4.5 – 9 hours post stroke onset, improve functional outcome at 90 days?
Continue reading »PreVent
In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?
Continue reading »SHoC-ED 3
In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?
Continue reading »Woolum
In patients with septic shock, does the administration of thiamine lead to more rapid lactate clearance and improved clinical outcomes?
Continue reading »COACT
In adult patients who have sustained an out of hospital arrhythmia-associated cardiac arrest without an ST-elevation myocardial infarction, is immediate angiography superior to delayed angiography in improving 90-day survival?
Continue reading »SUPERNOVA
Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?
Continue reading »ANDROMEDA-SHOCK
In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?
Continue reading »TICH-2
In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?
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