A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Emergency Medicine
In patients with primary moderate-large spontaneous pneumothorax does conservative management compared to interventional treatment result in acceptable rates of lung re-expansion at 8 weeks
Acceptable was defined as complete lung re-expansion at 8 weeks in 90% of patients
In patients hospitalised with symptomatic coronavirus disease 2019, does the administration of colchicine improve clinical & laboratory outcomes?
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In patients with gastrointestinal (GI) bleeding does high dose tranexamic acid (TXA) when compared to a placebo reduce mortality from GI bleeding?
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In patients with acute anterior ischaemic stroke, is endovascular thrombectomy alone, compared with endovascular thrombectomy preceded by intravenous alteplase, noninferior with respect to modified Rankin score at 90 days?
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In people who have high-risk or moderate-risk exposure to someone with confirmed COVID-19 infection, does taking hydroxychloroquine following the exposure compared to placebo reduce the incidence of a new illness compatible with COVID-19?
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In hospitalised adult patients with evidence of lower respiratory tract infection due to COVID-19, is remdesivir superior to placebo in shortening the time to recovery?
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In patients infected with SARS-CoV-2, what is the efficacy and safety of oral lopinavir–ritonavir?
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In patients with severe sepsis what is the sensitivity of blood cultures taken after the initiation of antimicrobial therapy?
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In patients requiring emergency out-of-hospital endotracheal intubation, is rocuronium non-inferior to suxamethonium in providing a successful first pass attempt?
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Does treatment with vitamin C, hydrocortisone, and thiamine lead to a more rapid resolution of septic shock compared with hydrocortisone alone?
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