Emergency Evidence Updates – March 2025
Randomised Controlled Trials
Combined ketamine and midazolam vs. midazolam alone for initial treatment of pediatric generalized convulsive status epilepticus (Ket-Mid study): A randomized controlled trial Pediatric Neurology
Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial The Lancet Respiratory Medicine
Comparison of the effects of vapocoolant spray and topical anaesthetic cream (lidocaine–prilocaine) on pain of intravenous cannulation: a randomised controlled trial Emergency Medicine Journal
Effects of adjunctive milrinone versus placebo on hemodynamics in patients with septic shock: a randomized controlled trial Annals of Medicine
Evaluation of the efficacy of low-dose Ketamine and dexmedetomidine compared to morphine for control of traumatic limb pain in the emergency department; a randomized clinical trial The Journal of Emergency Medicine
Vasopressin and Steroids in addition to Adrenaline in Cardiac Arrest (VAST-A) – A Randomised Pilot Study Resuscitation
Other Guidance/Reports
Analysis of the asthma scores recommended in guidelines for children presenting to the emergency department: a Pediatric Emergency Research Networks study Archives of Disease in Childhood
Faculty of prehospital care: consensus statement on the prehospital management of exertional heat illness Emergency Medicine Journal
Paracetamol in an emergency setting Archives of Disease in Childhood
PIER
- Chest Drain Insertion in a DGH setting (Thames Valley and Wessex ODN Guideline)
- CCLG Chemotherapy-Induced Nausea and Vomiting (Updated National Guideline)
RCEM
- Advisory Statement on Time Critical Medication Self- Administration in Emergency Departments (March 2025)
Cochrane
Nonsteroidal anti‐inflammatory drugs (NSAIDs) for acute renal colic
Ultrasound‐guided versus anatomic landmark‐guided percutaneous femoral artery access
Primary Research
Prehospital
Estimated caseload for a rotary wing prehospital Extra-Corporeal Cardio-Pulmonary Resuscitation service in North West England: a retrospective eligibility study Resuscitation Plus
“I can’t unsee him lying in my kitchen”: Understanding the Trauma of Family Members who Witness a Loved One’s Cardiac Arrest Resuscitation Plus
Intranasal analgesia for prehospital management of children in pain Journal of Paramedic Practice
Prehospital Antiplatelet Therapy In Patients With Out-Of-Hospital Cardiac Arrest Suspected Of Acute Coronary Syndrome Resuscitation
Prehospital paediatric trauma: equipping prehospital providers to deliver high-quality care Archives of Disease in Childhood
Should Anything Else Be Done Besides Prehospital CPR? The Role of CPR and Prehospital Interventions After Traumatic Cardiac Arrest The Journal of Emergency Medicine
Utilization of non-invasive ventilation before prehospital emergency anesthesia in trauma – a cohort analysis with machine learning Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
General
A framework and analytical exploration for a data-driven update of the Sequential Organ Failure Assessment (SOFA) score in sepsis Critical Care and Resuscitation
Artificial Intelligence as a Language Barrier Application in a Simulated Health Care Setting – A Proof-of-Concept Study Pediatric Emergency Care
Developing and Testing a Multimodal Intervention to Decrease Violence and Increase Perceptions of Safety in the Emergency Department: A Longitudinal Study Journal of Emergency Nursing
Drivers of low-value diagnostic tests in emergency medicine practice: a qualitative descriptive study Emergency Medicine Journal
Impact of Registered Nurse Staffing, Workload, and the Practice Environment on Burnout in Emergency Nurses Journal of Emergency Nursing
Improving the Care of Transgender/Gender-Nonconforming Patients in the Emergency Department Through Quality Improvement: An Educational Intervention for Emergency Clinicians Journal of Emergency Nursing
Global health experience of staff working in UK emergency care: a reflexive thematic analysis Emergency Medicine Journal
Nurses’ lived experiences of self-control in emergency settings: a qualitative study BMC Emergency Medicine
Penetrating nail gun injuries: Role of antibiotics and surgical management Trauma
Reproducibility of the Manchester Triage System: a multicentre vignette study Emergency Medicine Journal
The Introduction of Flow Facilitators- a targeted Wellness Initiative in the Emergency Department The Journal of Emergency Medicine
Paediatrics
A Novel Streamlined Triphasic Approach to Training Pediatric Emergency Staff for Ultrasound-Guided Peripheral Intravenous Access Journal of Emergency Nursing
Caffeine overdose resulting in seizure-like activity and rhabdomyolysis in a child: a case report The Journal of Emergency Medicine
Can we trust naked eye assessments of the capillary refill test in children? An experimental study BMC Emergency Medicine
Developing the Standardized Workload Assessment Metric for Pediatric Emergency Departments – Initial Steps Using a Modified Delphi Method Pediatric Emergency Care
Enhancing clinical risk assessment in pediatric blunt abdominal trauma: A novel scoring system using ultrasound and laboratory data BMC Emergency Medicine
Evaluation of nasogastric tube location using point-of-care ultrasonography in paediatric patients Emergency Medicine Journal
Glycerol intoxication syndrome in young children, following the consumption of slush ice drinks Archives of Disease in Childhood
Guanfacine exposure in paediatric and adolescent patients: A multicentre retrospective review Emergency Medicine Australasia
Manchester Triage System as a Predictive Model for Early Placement of Peripheral Venous Catheters in a Pediatric Emergency Department: A Cross-Sectional Study Journal of Emergency Nursing
Minimal Sedation Use for Laceration Repair in the Pediatric Emergency Department The Journal of Emergency Medicine
Ophthalmology Examinations in Children With Skull Fractures and Underlying Focal Hemorrhage Pediatric Emergency Care
Poisoning in adolescents in the UK: a review of enquiries to the National Poisons Information Service Archives of Disease in Childhood
Predicting Future Acute Care Visit Risk in Kids With Asthma (PARKA) – A Nested Cohort Study Pediatric Emergency Care
Prehospital and Resuscitation Factors Associated With Favorable Pediatric Drowning Outcomes Pediatric Emergency Care
These Hips Don’t Lie: Deep Vein Thrombosis in an Adolescent With an Inferior Vena Cava Anomaly Pediatric Emergency Care
Unveiling Hidden Fractures: Point of Care Ultrasound in Diagnosing Pediatric Clavicle Fractures Missed by x-ray Pediatric Emergency Care
Adults
A Case Series: Ultrasound-Guided Superficial Cervical Plexus Nerve Block for Musculoskeletal Neck Pain The Journal of Emergency Medicine
Accuracy of colour Doppler ultrasound for nasogastric tube placement in emergency department: A prospective observational study Emergency Medicine Australasia
Acute Delirium From Urinary Retention in Elderly Women With Alzheimer’s Disease: A Case of Female Cystocerebral Syndrome Journal of Emergency Nursing
Coma as the sole initial manifestation of levothyroxine intoxication: a case report The Journal of Emergency Medicine
Comparison of the effects of vapocoolant spray and topical anaesthetic cream (lidocaine–prilocaine) on pain of intravenous cannulation: a randomised controlled trial Emergency Medicine Journal
Compliance Evaluation with ChatGPT for Diagnosis and Treatment in Patients Brought to the ED with a Preliminary Diagnosis of Stroke Prehospital Emergency Care
Comprehensive Analysis of Heart Failure Subtypes Presenting at Emergency Department for Acute Heart Failure Management Journal of Emergency Nursing
Disposable female urinal bottle (the UniWee) improves patient experience for immobile women with lower limb fractures Emergency Medicine Journal
Duration of resuscitation, regain of consciousness and histopathological severity of hypoxic-ischemic encephalopathy after cardiac arrest Resuscitation Plus
Effect of change of high-sensitivity troponin I assay on emergency department diagnosis and disposition of patients with possible acute coronary syndrome Emergency Medicine Australasia
Effect of non-invasive rhythm control on outcomes in patients with first diagnosed atrial fibrillation presenting to an emergency department BMC Emergency Medicine
Esophageal Induced Acute Airway Obstruction The Journal of Emergency Medicine
Evaluation of a team-based approach for emergency department patients with time critical intracranial conditions Emergency Medicine Australasia
Hypoxemia in trauma patients receiving two different oxygen strategies: a TRAUMOX2 substudy Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Evolution of Secondary Findings in Acute Cholecystitis: A Temporal Analysis from Point-of-Care Ultrasound to Subsequent Imaging The Journal of Emergency Medicine
Factors associated with early return visits to the emergency department in patients with vaso-occlusive crisis BMC Emergency Medicine
Implementation of a 90-minute gonorrhea/chlamydia test decreases antibiotic under–and overtreatment in female emergency department patients The Journal of Emergency Medicine
Improving Initial Management of Septic Patients: Comparing IV Push versus IV Piggyback Antibiotics The Journal of Emergency Medicine
Outcomes of Older Adults With Delirium Discharged From the Emergency Department Annals of Emergency Medicine
The Need for SPEED: Sonography for Pulmonary Embolism in the Emergency Department The Journal of Emergency Medicine
Unselected cardiac troponin testing and the diagnosis of myocardial infarction in the emergency department BMC Emergency Medicine
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
