Emergency Evidence Updates – February 2025

Randomised Controlled Trials

Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study  The Lancet

PEAChY-O: Pharmacological Emergency Management of Agitation in Children and Young People: A Randomized Controlled Trial of Oral Medication  Annals of Emergency Medicine

 

Other Guidance/Reports

Topical analgesia during needle-related procedures in children: a clinical practice guideline  Archives of Disease in Childhood

 

Primary Research

Prehospital

Amiodarone dose in patients with shockable out-of-hospital cardiac arrest  Resuscitation

Cardiac arrest survivors’ self-reported cognitive function, and its association with self-reported health status, psychological distress, and life satisfaction—a Swedish nationwide registry study  Resuscitation

Characteristics, diagnostic accuracy, and safety in patients receiving selective prehospital thrombolysis in out-of-hospital cardiac arrest: a retrospective cohort study  Resuscitation Plus

Clinical factors associated with the use of NIV in the pre-hospital setting in adult patients treated for acute COPD exacerbation: a single-center retrospective cohort study  BMC Emergency Medicine

Comparison between point-of-care international normalised ratio, COAST, TICCS and truncated FibAT scores to rule in clinically significant hypofibrinogenaemia in the prehospital setting  Emergency Medicine Journal

Critical interventions, diagnosis, and mortality in children treated by a physician-manned mobile emergency care unit  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Diastolic blood pressures and end tidal carbon dioxides during cardiopulmonary resuscitations and their association with outcomes in adult out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the Augmented Medication CardioPulmonary Resuscitation (AMCPR) trial  Resuscitation

Factors influencing paramedic conveyance decisions when attending children with minor head injury: a qualitative study  Emergency Medicine Journal

Predictive performance of prehospital trauma triage tools for resuscitative interventions within 24 hours in high-risk or life-threatening prehospital trauma patients  BMC Emergency Medicine

The impact of alternate defibrillation strategies on time in ventricular fibrillation  Resuscitation

Time to Bystander CPR and Survival for Witnessed Out-of-Hospital Cardiac Arrest  Resuscitation

Understanding cardiac arrest dispatch of physician-paramedic critical care prehospital teams: a survey-based evaluation  Emergency Medicine Journal

 

General

ASA score is an independent predictor of 1-year outcome after moderate-to-severe traumatic brain injury  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Changes in the Neurological Status From 30 to 90 days post-Cardiac Arrest by Age: A Nationwide Retrospective Observational Study  Resuscitation Plus

Chest compression synchronized ventilation during prolonged experimental cardiopulmonary resuscitation improves oxygenation but may cause pneumothoraces  Resuscitation Plus

Comparison of mechanical restraint use in a metropolitan ED after system change: A before and after analysis  Emergency Medicine Australasia

Criteria for early discharge of drowning patients from the emergency department  Emergency Medicine Australasia

Effectiveness of a Web-Based Training Intervention in Teaching Emergency Physicians First-Trimester Point-of-Care Ultrasound Image Interpretation  Annals of Emergency Medicine

Improving Left Ventricular Assist Device Competency in Emergency Nurses Using Quarterly Skills Check and Simulation  Journal of Emergency Nursing

Performance of machine learning models in predicting difficult laryngoscopy in the emergency department: a single-centre retrospective study comparing with conventional regression method  BMC Emergency Medicine

Practitioner experiences of developing and implementing two UK ED-based hospital violence intervention programmes: a process evaluation  Emergency Medicine Journal

Predicting high-risk return at emergency department presentation for patients who undergo short-term revisits: the HANDLE-24 score  BMC Emergency Medicine

Self-reported knowledge and attitudes surrounding care of LGBTQIA+ patients in the emergency department  Emergency Medicine Australasia

What should be documented for an anterior shoulder dislocation? A Delphi study  Emergency Medicine Journal

 

Paediatric

A Prediction Rule to Identify Children and Young Adults at Low Risk for Myocarditis  Pediatric Emergency Care

Accuracy of Visual Estimation of Left Ventricular Ejection Fraction Compared With Echocardiography in Children  Pediatric Emergency Care

Cardiac Point-of-Care Ultrasound Findings in Multisystem Inflammatory Syndrome in Children in the Pediatric Emergency Department  Pediatric Emergency Care

Clinical Features and Management Strategies in Children With Mycoplasma Pneumoniae  Pediatric Emergency Care

Development of a Pediatric Age-Based and Weight-Adjusted Nomogram for Bladder Volumes Associated With Successful Completion of Transabdominal Pelvic Ultrasound (TPU)  Pediatric Emergency Care

Drivers of Bronchodilator Use in Bronchiolitis – Analyzing Treatment Trends From Pediatric Emergency Department Practices  Pediatric Emergency Care

Emergency Management of Animal-Related Injuries in Children – An Observational Multicenter Italian Study  Pediatric Emergency Care

Factors associated with extended length of stay for paediatric mental health presentations to EDs in South Western Sydney, Australia  Emergency Medicine Australasia

Pediatric cylindrical battery ingestion  Endoscopy International Open

POCUS Standoff: Comparing Ultrasound Interfaces for Soft Tissue Foreign Body Imaging  Pediatric Emergency Care

POCUS the Pelvis: A Case Series of Timely Diagnoses in Pediatric Patients With Abdominal Pain  Pediatric Emergency Care

Point-of-Care Ultrasound Diagnosis of Restrictive Cardiomyopathy in a 3-Year-Old Patient  Pediatric Emergency Care

Psychological Experiences of Primary Caregivers of Adolescent and Young Adult Patients Who Lived Through a Suicide Attempt by Poisoning in the Emergency Department: A Qualitative Study  Journal of Emergency Nursing

Severe accidental poisonings in children: a British Paediatric Surveillance Unit nationwide prospective study  Archives of Disease in Childhood

Zipper Entrapment of the Eyelid with a Unique Removal Technique  The Journal of Emergency Medicine

 

Adult

A Case of Concurrent Metformin-Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis  The Journal of Emergency Medicine

A pilot trial exploring the use of music in the emergency department and its association with delirium and other clinical outcomes  Emergency Medicine Australasia

Choice of Intravenous Fluid for Resuscitation in Diabetic Ketoacidosis  NEJM

Clinical and demographic factors associated with increased risk of postpartum readmission among patients presenting to the emergency department by 6 weeks postpartum  The Journal of Maternal-Fetal & Neonatal Nursing

Embolization of the Middle Meningeal Artery for Chronic Subdural Hematoma  NEJM

Floor of the Mouth Ultrasound (FOMUS) Assessment in Ludwig’s Angina  The Journal of Emergency Medicine

Impact of a POCUS-first versus CT-first approach on emergency department length of stay and time to surgical consultation in patients with acute cholecystitis: a retrospective study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode  Journal of Emergency Nursing

Incidence and risk factors for delayed intracranial hemorrhage after mild brain injury in anticoagulated patients: a multicenter retrospective study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

In-hospital stay of anemic patients in the ED with/without transfusion: a single-center propensity-matched study  BMC Emergency Medicine

Optimizing ultrasound methods for determining central venous catheter tip position  The Journal of Emergency Medicine

Painful Left Bundle Branch Block Syndrome Diagnosed in the Emergency Department  The Journal of Emergency Medicine

Perigastric appendagitis, a rare cause of abdominal pain: A case report  The Journal of Emergency Medicine

Predictive value of ionized calcium level for sinus rhythm conversion in adenosine treatment for paroxysmal supraventricular tachycardia  The Journal of Emergency Medicine

Short-Term Risk of Adverse Cardiac Events Among Emergency Department Patients Placed in an Observation Unit for Cardiac Testing  The Journal of Emergency Medicine

Ultrasound-Guided Pectoralis Block for Incision and Drainage of Chest Wall Abscess in the Emergency Department  The Journal of Emergency Medicine

Ultrasound-Guided Serratus Anterior Plane Block for Acute Zoster Pain in an Immunocompromised Heart Transplant Patient in the Emergency Department  The Journal of Emergency Medicine

 

Metadata

Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash

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