Bradford
In patients with aneurysmal subarachnoid haemorrhage does induced hypermagnesaemia reduce the incidence of cerebral artery vasospasm?
Continue reading »Author: David Slessor
Pascall
In patients who were admitted to the ICU what litigation claims were made and what was their cost?
Continue reading »Motov
In patient with acute, moderate to severe pain in the ED, does ketamine compared with morphine, reduce pain scores by an equivalent amount?
Continue reading »Idarucizumab for Dabigatran Reversal
In patients taking dabigatran, who present with serious bleeding or require urgent surgery/intervention is idarucizumab safe and efficacious for the reversal of anticoagulation?
Continue reading »Niemann
In organ donors, following diagnosis of brainstem death, does therapeutic hypothermia decrease delayed graft function in kidney recipients?
Continue reading »SHOCK 2
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial IABP-SHOCK II Trial Investigators.NEJM;2012,367(14)1287-96, DOI: 10.1056/NEJMoa1208410 Clinical Question In patients with acute MI and cardiogenic shock, does intraaortic balloon counterpulsation (IABP) vs. medical therapy alone improve mortality? Design Randomised controlled trial Randomisation performed centrally via internet based program […]
Continue reading »BEST:TRIP
In patients with severe traumatic brain injury does monitoring intracranial pressure improve mortality and improve neurological function?
Continue reading »FEAST
In paediatric patients with severe febrile illnesses, in a resource limited setting, do fluid boluses with albumin vs. saline vs. no fluid boluses affect mortality?
Continue reading »DESTINY II
In older patients with malignant middle cerebral artery infarction does early hemicraniectomy, compared with standard care, improve survival without severe disability?
Continue reading »Kumar
In patients with septic shock, what is the relationship between appropriateness of initial empiric antimicrobial therapy and survival?
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