Gujjar
In patients with status epilepticus (SE) and cluster attacks of seizures, (CS) does IV levetiracetam vs. IV phenytoin improve rate of control of seizures?
Continue reading »Author: David Slessor
ADRENAL
In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
Continue reading »CURE
In patients with acute coronary syndromes without ST elevation, does clopidogrel + aspirin, compared with aspirin alone, reduce a composite outcome of death from cardiovascular causes, acute myocardial infarction and stroke?
Continue reading »ICE-CUB 2
In critically ill patients aged over 75 years, does a recommendation for systematic ICU admission compared with standard care reduce 6 month mortality?
Continue reading »Reconnect
In critically ill adult patients who pass a spontaneous breathing trial (SBT), does 1-hour rest compared with immediate extubation reduce re-intubation rates at 48 hours?
Continue reading »60/60 sign for Acute PE
In patients with suspected acute pulmonary embolism, do echo features of disturbed right ventricular ejection allow accurate diagnosis?
Continue reading »SHENFU
In patients with in-hospital cardiac arrest, does Shenfu (a traditional Chinese
medicine), improve 28 day mortality?
TTM 48
In adults with out of hospital cardiac arrest (OOHCA) due to a presumed cardiac cause, who are post ‘return of spontaneous circulation’ (ROSC), does cooling to 33°C for 48 hours, compared with 24 hours, improve improved neurological outcomes at 6 months?
Continue reading »Hernandez 2
In critically ill patients who are at high risk for re-intubation, is high flow nasal oxygen non-inferior to non-invasive ventilation in reducing re-intubation and post-extubation respiratory failure?
Continue reading »TRICOP
In cancer patients with septic shock does a restrictive vs. a liberal transfusion threshold reduce 28 day mortality?
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